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Oral Minoxidil: The 90s Hair Loss Drug Making A Powerful Comeback

Originally a topical treatment, minoxidil is now being prescribed as a low-dose pill for hair regrowth, offering a more convenient solution for men and women.

Pratibha by Pratibha
March 20, 2025
Reading Time: 2 mins read
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Oral minoxidil emerges as convenient treatment for hair loss, dermatologists say. (Freepik)

The latest innovation in hair loss treatment isn’t new at all—it’s a repurposed medication that first gained popularity in the 1990s. Minoxidil, commonly known as Rogaine, was initially introduced as a topical solution to combat thinning hair. Now, dermatologists are increasingly prescribing it in a low-dose pill form, claiming it offers a more effective and hassle-free alternative.

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Minoxidil was originally developed in the 1970s as a blood pressure medication, but doctors noticed a surprising side effect—patients experienced increased hair growth. In 1988, the FDA approved it as the first drug for male pattern baldness, followed by a lower-dose version for women in 1991. While the topical solution gained immense popularity through aggressive marketing, many users found it inconvenient and messy to apply daily.

Why Dermatologists Are Turning to Oral Minoxidil

Recent studies suggest that oral minoxidil may be just as effective—if not more—than its topical counterpart. When ingested, the drug is absorbed more efficiently, increasing blood circulation to the scalp and extending the hair’s growth phase.

“By increasing blood flow to the scalp, it signals hairs to stay in their growth phase longer,” explains Dr. Adam Friedman, chair of dermatology at George Washington University. “We’re trying to keep those hairs in that phase as long as possible.”

Aside from its potential effectiveness, oral minoxidil offers a more convenient option for patients. Unlike the liquid formulation, which requires daily application using a dropper, the pill form is taken once a day, reducing the likelihood of users abandoning treatment.

How Safe Is Oral Minoxidil?

Though generally well-tolerated, oral minoxidil can cause side effects such as dizziness, rapid heartbeat, and swelling in the legs. However, dermatologists typically prescribe very low doses—often a fraction of the lowest available blood pressure pill—to minimize risks. Women are usually advised to take just a quarter of a pill, while men may take half.

Despite its benefits, oral minoxidil is not FDA-approved for hair loss. Since the drug’s patent has expired, pharmaceutical companies have little financial incentive to fund the costly studies required for approval. Instead, dermatologists prescribe it off-label using the existing blood pressure medication.

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The Role of Telehealth in Expanding Access

Telehealth platforms like Hims and Ro have played a significant role in making oral minoxidil more accessible. These services allow patients to obtain prescriptions online after answering a few medical history questions, bypassing traditional doctor visits. The process is quick, convenient, and discreet, with prescriptions delivered straight to customers’ doors.

However, some dermatologists warn against relying solely on online services. “I recommend seeing a board-certified dermatologist who can properly assess your hair loss, medical history, and potential side effects,” says Dr. Susan Taylor of the University of Pennsylvania. A thorough in-person consultation ensures that patients receive the right treatment tailored to their individual needs.

A Cost-Effective Solution for Hair Loss

One of the biggest advantages of oral minoxidil is its affordability. Since the drug is available as a low-cost generic, a month’s supply can cost as little as $5. “Not a single patient has complained about the cost of this medication,” says Dr. Luiz Garza of Johns Hopkins University.

For those looking for a budget-friendly, low-maintenance alternative to topical treatments, oral minoxidil may be the answer. While research is still ongoing, the growing number of dermatologists recommending it suggests that this once-forgotten drug could become a game-changer in the fight against hair loss.

 

Tags: dermatologistsFDA approvalHair loss treatmenthair regrowthhair thinning solutionsminoxidiloral minoxidiltelehealth
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Pratibha

Pratibha

A passionate news person, trying to reflect her views on the recent happenings around the globe, bringing you a nuanced perspective and keeping the ethics of journalism alive in the process. My journey started in an international newsroom, where I have covered major events and been to the roots of them.  The  South-Asian region has also caught my interest, where I have covered more of the features and cultural side of the South-Asian countries. As a journalist dedicated to ethical reporting and with a personal interest in exposing hidden narratives, I aim to offer complex perspectives that enhance comprehension of the modern, globalized world.

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